(Sr.) Director, DMPK, Orexin Program - Remote

Overview

The Director/Senior Director, DMPK will be responsible for leading the Drug Metabolism and Pharmacokinetics (DMPK) activities across the Orexin agonist portfolio, guiding the strategy and execution of DMPK studies from early discovery through clinical development for small molecule drugs.

In Short

• Provide strategic direction and oversight for DMPK data delivery.
• Develop and implement DMPK strategies aligned with drug discovery objectives.
• Collaborate with project teams and functional groups.
• Oversee design and execution of DMPK studies.
• Interpret DMPK data and present findings.
• Review BA and TK reports and conduct analysis.
• Prepare DMPK sections for regulatory submissions.
• Build relationships with CROs and external partners.

Requirements

• PhD in Pharmacokinetics, Pharmaceutical Sciences, or related field.
• 10+ years of small molecule DMPK experience.
• In-depth knowledge of DMPK principles.
• Adept in DMPK modeling and simulation tools.
• Experience with US and EU regulatory submissions.
• Strong leadership and mentoring skills.

Benefits

• Remote work opportunity.
• Infrequent travel to headquarters.
• Diverse and inclusive work environment.