Resolve to Save Lives (RTSL) is a global public health organization based in the United States, dedicated to preventing 100 million deaths from heart disease and enhancing epidemic safety worldwide. Since its inception in 2017, RTSL has collaborated with governments of low- and middle-income countries, multilateral agencies, academic institutions, and civil society to implement effective policies and programs aimed at controlling hypertension, reducing sodium intake, eliminating artificial trans fats, and strengthening epidemic prevention systems.