Director/Senior Director, Clinical Program Management - Remote

Overview

Adverum Biotechnologies, Inc. is a mission-driven clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures to restore vision and prevent blindness. Leveraging the research capabilities of its proprietary intravitreal (IVT) platform, Adverum is developing durable, single-administration therapies designed to be delivered in physicians’ offices to eliminate the need for frequent ocular injections to treat these diseases. By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe.

In Short

• Oversees clinical programs across Adverum, engaging with key functional representatives to understand status and key risks, escalating accordingly.
• Develops and implements overall clinical program management strategy across Adverum in collaboration with PMO Lead and Functional Leads.
• Plans, aligns, communicates, and coordinates detailed and high-level cross-functional Phase 3 study timelines.
• Liaises with cross-functional teams to ensure alignment with integrated Phase 3 timelines and fit within overall program timelines.
• Resolves timeline discussions as they arise – balancing team ability to deliver with study objectives and timelines.
• Ensures all activities for Phase 3 start-up and operational timelines remain on track, escalating key risks and timeline clashes to program and functional leadership.
• Drives coordination of all team members to ensure timely planning, mapping, communicating, and completion of sequential and parallel activities.
• Maintains critical path to key Study and Program milestones and ensures that target deliverable times are well defined and met.
• Applies best practices for clinical conduct to all facets of study, coordinating with Clinical QA as needed.
• Evaluates impact of changes to Phase 3 design or strategy, whether driven by external or internal forces.

Requirements

• Bachelor’s degree in life sciences, healthcare, or a related field required. Advanced degree (MS, PharmD, or PhD) preferred.
• Minimum of 10-12+ years of experience in clinical program management or clinical trial operations within the biotech, pharmaceutical, or CRO industry.
• Proven experience managing complex, multi-center clinical programs from initiation to close-out.
• Proficiency with project management tools and software, such as MS Project, GAANT charts or equivalent.
• Strong understanding of clinical trial regulations (FDA, EMA, ICH-GCP) and regulatory requirements.
• Ability to analyze and interpret clinical data and program metrics to inform strategic decisions.

Benefits

• Competitive salary and benefits package.
• Opportunity to work on innovative gene therapy projects.
• Collaborative and mission-driven work environment.
• Professional development opportunities.
• Impactful work that contributes to restoring vision and preventing blindness.