Clinical Trial Manager - Remote

Overview

Caribou Biosciences is a leading clinical-stage CRISPR genome-editing biopharmaceutical company dedicated to developing transformative therapies for patients with devastating diseases. Our next-generation genome-editing technology enables superior precision to develop cell therapies that are armored to potentially improve activity against diseases. We believe the future of cell therapy is off-the-shelf, and we are advancing our pipeline of off-the-shelf, or allogeneic, cell therapies from our CAR-T cell therapy platform as readily available treatments for patients with hematologic malignancies.

In Short

• Responsible for execution and oversight of clinical trials from start-up through close-out.
• Ensure alignment with ICH-GCP, applicable regulations, internal SOPs, and protocols.
• Collaborate cross-functionally and manage vendors and sites.
• Support feasibility assessments, site selection, and study start-up activities.
• Oversee site activation, patient enrollment, and trial execution activities.
• Identify and mitigate risks through proactive trial-level risk assessments.
• Develop and deliver training to investigators, sites, and internal teams.
• Partner closely with internal stakeholders to align on trial design and execution.
• Maintain an inspection-ready Trial Master File (TMF).
• Manage trial budgets and forecasting in collaboration with Finance.

Requirements

• BS in Life Sciences or related field with 6+ years clinical operations experience.
• Prior sponsor-side clinical trial management experience.
• Demonstrated proficiency in clinical trial oversight, including CRO and vendor management.
• Strong command of ICH-GCP and regulatory requirements.
• Advanced skills in Microsoft Office Suite and clinical systems (e.g., CTMS, eTMF).
• Excellent organizational, problem-solving, and interpersonal communication skills.

Benefits

• Comprehensive compensation package, including competitive salary, bonus, and equity.
• Generous paid vacation time, in addition to company-observed holidays and floating holidays.
• Excellent medical, dental, and vision insurance.
• 401(k) retirement savings plan with matching employer contributions.
• Employee stock purchase plan (ESPP).
• Tuition reimbursement program.