Senior/Staff Bioinformatics Production Scientist - Remote

Overview

We are seeking a highly motivated, results-oriented, and collaborative individual to join our Bioinformatics and Analytics team as a Senior/Staff Bioinformatics Production Scientist. In this role, you will combine genomics expertise with strong production engineering skills to design and implement robust, scalable computational pipelines for large-scale NGS data processing and interpretation.

This role is critical in advancing our bioinformatics capabilities to ensure best-in-class performance for Twist Bioscience’s production pipelines. You will be responsible for architecting high-throughput workflows, maintaining reliable bioinformatics infrastructure, and collaborating with Field Application Scientists (FAS) to optimize pipelines that directly support customer needs and field operations.

In Short

• Develop and maintain production-grade bioinformatics pipelines for NGS data processing.
• Ensure pipelines are scalable, reproducible, and optimized for high-throughput sequencing data.
• Integrate best practices in software development, including CI/CD and containerization.
• Work directly with Field Application Scientists to understand their workflow needs.
• Lead architectural decisions for bioinformatics workflows in cloud-based or on-prem environments.
• Collaborate with DevOps teams to maintain monitoring and alerting systems.
• Design and implement data storage solutions for large-scale genomic datasets.
• Partner with FAS teams to troubleshoot pipeline-related issues.
• Work closely with wet-lab scientists to provide bioinformatics insights.
• Collaborate with other Senior Bioinformatics Scientists to ensure consistency in data processing pipelines.

Requirements

• Master’s degree with 6–8 years of industry experience, or a Ph.D. with 3+ years of industry experience in Bioinformatics or related field.
• Experience designing and optimizing production-scale bioinformatics pipelines for NGS data.
• Strong understanding of workflow orchestration frameworks.
• Hands-on experience with large-scale genomic data processing.
• Proficiency in Python and familiarity with containerization and cloud platforms.
• Ability to work closely with Field Application Scientists.
• Strong troubleshooting skills in a high-throughput environment.

Benefits

• Opportunity to work in a cutting-edge field of bioinformatics.
• Collaborative and innovative work environment.
• Engagement with cross-functional teams.
• Contribution to impactful projects in genomics.