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Senior Scientist, Epigenetics - Remote

Posted 5 days ago
All others
Full Time
Worldwide

Overview

Conception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team to make this vision a reality.

In Short

  • Define the key questions linking epigenetic signature to germline competence and meiotic progression.
  • Benchmark our cells against in vivo counterparts and identify discrepancies.
  • Derive and benchmark new pluripotent cell lines.
  • Collaborate with a computational biology scientist for cross-species comparisons.
  • Drive experiments with our cell engineering team to explore epigenetic perturbations.
  • Design and interpret assays of epigenetic state.

Requirements

  • PhD in epigenetics, developmental biology, genetics, stem cell biology or related field.
  • Strong publication record on epigenetics of pluripotency or early development.
  • Hands-on human ES/iPSC culture experience.
  • Deep expertise in histone modification and DNA methylation profiling.
  • Experience designing and interpreting datasets like ChIP-seq, CUT&RUN, ATAC-seq.
  • Working knowledge of X-chromosome dynamics and genomic imprinting.
  • Ability to collaborate with computational biologists.

Benefits

  • Define and accelerate critical programs that could transform human reproduction.
  • Operate with autonomy inside a growing biotech company.
  • Work alongside passionate scientists tackling exciting frontiers in biology.
Conception logo

Conception

Conception is an innovative startup focused on groundbreaking research to generate viable human eggs from induced pluripotent stem cells (iPSCs). With the potential to revolutionize reproductive health, their work aims to eliminate age limits on motherhood, facilitate genetic screening of eggs, and enable same-sex couples to reproduce. Well-funded and connected in Silicon Valley, Conception offers a collaborative research environment, competitive pay, equity, and excellent healthcare benefits, all while striving for meaningful advancements in the field of bioinformatics and reproductive technology.

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